PL-21 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

PL-21 cell line细胞株

Synonyms PL21
Accession CVCL_2161
Resource Identification Initiative To cite this cell line use: PL-21 (RRID:CVCL_2161)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 48-64 hours (PubMed=6362749); ~40-50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations FLT3 internal tandem duplication (FLT3-ITD) (PubMed=12529668).
Heterozygous for KRAS p.Ala176Val (c.437C>T) (CCLE; Cosmic-CLP).
Heterozygous for TP53 p.Pro36fs*8 (c.107delC) (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin % genome
African 0
Native American 1.5
East Asian, North 78.62
East Asian, South 18.83
South Asian 0
European, North 0
European, South 1.05
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; JCRB; PubMed=25877200

Markers:
Amelogenin X,Y
CSF1PO 11,12
D3S1358 15
D5S818 10
D7S820 12,13
D8S1179 10
D13S317 8,11
D16S539 11,13
D18S51 12,13
D21S11 29,30
FGA 21,24
Penta D 11,13
Penta E 5,17
TH01 9
TPOX 9,11
vWA 14,18

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