Mus musculus inositol 1,4,5-trisphosphate receptor 1 (Itpr1) gene基因表达质粒敲除载体 BioVector NTCC质粒载体菌种细胞基因保藏中心

Mus musculus inositol 1,4,5-trisphosphate receptor 1 (Itpr1) gene基因表达质粒敲除载体

RefSeq NM_010585.5, NP_034715.3RefSeq Size 9875 bpRefSeq ORF 8250 bpLocus ID 16438Gene Summary Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (PubMed:23542070). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net