PC3 (MYC-amplified) cell line人前列腺癌细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

PC3 (MYC-amplified) cell line人前列腺癌细胞株

Product category
Human cells
Organism
Homo sapiens, human
Morphology
epithelial
Tissue
Prostate
Disease
Adenocarcinoma; Grade IV
Applications
3D cell culture

Specific applications
This cell line is a suitable transfection host.

Growth properties
Adherent
Derivation
The PC-3 was initiated from a bone metastasis of a grade IV prostatic adenocarcinoma from a 62-year-old male Caucasian.
Age
62 years
Ethnicity
White
Gender
Male
Clinical data
The PC-3 was initiated from a bone metastasis
Karyotype
The line is near-triploid with a modal number of 62 chromosomes. There are nearly 20 marker chromosomes commonly found in each cell; and normal N2, N3, N4, N5, N12, and N15 are not found. No normal Y chromosomes could be detected by Q-band analysis.
Tumorigenic
Yes;
Yes, in semi-solid medium
Yes, tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 10(7) cells.
Metastatic
Bone
Antigen expression
HLA A1, A9
Genes expressed
HLA: (A1; A9)
Comments
The cells exhibit low acid phosphatase and testosterone-5-alpha reductase activities.

Complete medium
The base medium for this cell line is F-12K Medium. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%.
Temperature
37°C
Atmosphere
95% Air, 5% CO2

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