Caco2-BBE cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

Caco2-BBE cell line细胞株

Cell line name C2BBe1
Synonyms C2BBE1; C2BBe 1; Caco-2/BBe 1; Caco-2/BBe; Caco-2BBe; Caco-2BBE; Caco-2 BBe; Caco2-BBE; Caco2BBe; Caco2BBE; CACO2BBE; BBE

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: 44 hours (PubMed=25984343).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative phosphoproteome analysis.
Omics: Deep quantitative proteome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Colon.
Sequence variations Mutation; HGNC; 583; APC; Simple; p.Gln1367Ter (c.4099C>T); ClinVar=VCV000376060; Zygosity=Homozygous (ATCC; Cosmic-CLP; DepMap).
Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly245Ala (c.734G>C); Zygosity=Heterozygous (Cosmic-CLP; DepMap).
Mutation; HGNC; 6770; SMAD4; Simple; p.Asp351His (c.1051G>C); ClinVar=VCV000375998; Zygosity=Homozygous (Cosmic-CLP; DepMap).
Mutation; HGNC; 11998; TP53; Simple; p.Glu204Ter (c.610G>T); ClinVar=VCV000977783; Zygosity=Homozygous (Cosmic-CLP; DepMap).
Genome ancestry Source: PubMed=30894373

Origin % genome
African 0
Native American 0
East Asian, North 1.84
East Asian, South 0.11
South Asian 0
European, North 57.43
European, South 40.62
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0025 (Caco-2)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line

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