BEL-A cell line布里斯托尔成人红细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

BEL-A cell line布里斯托尔成人红细胞株

NTCC® BEL-A (Bristol Erythroid Line Adult) "immortal" cells were created by researchers at BioVector NTCC Inc. using blood from volunteers who donated for the purpose of this study. Science Alert reports, "To create these 'immortal' cells, [the researchers] effectively trapped the adult stem cells in an early stage of development, which means they can divide and create red blood cells forever without dying, which avoids the need for repeat donations." Such findings will enable scientists to more easily and quickly harvest and maintain large amounts of red blood cells.

The purpose of red blood cells is to carry oxygen throughout the body -- this is especially important for sickle cell warriors, as sickled red blood cells can disrupt this flow and block blood vessels, causing pain and potentially, a crisis. "Cultured red blood cells provide such an alternative and have potential advantages over donor blood, such as reduced risk of infectious disease transmission, and as the cells are nascent, the volume and number of transfusions administered to patients requiring regular transfusions (sickle cell disease, thalassaemia myelodysplasia, certain cancers) could be reduced, ameliorating the consequences of organ damage from iron overload," explains a recent article from Nature Communications.

Clinical trials for the artificial blood created by BEL-A cells are expected to begin by the end of 2017. If everything goes well and the product is proven safe and effective in humans, it can begin being used to treat people in need all over the world.

Supplier来源:BioVector NTCC Inc.
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