AG10032 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C; XPC Skin, Arm Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® AG10032 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C; XPC Skin, Arm Cell Line
色素性干皮病，补充组 C； XPC细胞株
Description描述：The American Indian donor (XP23BE) is clinically affected with features of sun sensitivity, freckling, over 50 skin cancers, and an astrocytoma of the spinal cord. The donor also has a cystic bone disorder of unknown origin. He has consanguineous parents and a sibling who died of X P. The biopsy was taken ante-mortem on 5/16/88 from the left upper arm. The culture was initiated using explants of minced skin tissue. The cell morphology is fibroblast-like. A lymphoblast culture from same donor is AG10033. Donor subject is homozygous for an A>C transversion at -2 in intron 5.1 of the XPC gene (IVS5.1-2A>C) resulting in an 83 bp insertion of intron 5.1 with a stop 34 codons downstream.
Category分类：Fibroblast
ID编号:NTCC®-AG10032
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: American Indian/Alaska Native
Age年龄:21 YR
Gender性别:Male
Cell Type细胞类型: XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C; XPC
Affected State:Yes
Product:Fibroblast
Gene:XPC
Mutations突变:IVS5.1-2A>C
Ethnicity:
Family:1150
Relationship:proband
Karyotype:46,XY[18]
Tissue Type组织来源:Skin
Complete Growth Medium完全培养基: BioVector® Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
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