GM19203 YORUBA IN IBADAN, NIGERIA | CYTOCHROME P450, SUBFAMILY IIC, POLYPEPTIDE 19; CYP2C19 B-Lymphocyte Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM19203 YORUBA IN IBADAN, NIGERIA | CYTOCHROME P450, SUBFAMILY IIC, POLYPEPTIDE 19; CYP2C19 B-Lymphocyte Cell Line
尼日利亚伊巴丹的约鲁巴语 |细胞色素 P450，亚族 IIC，多肽 19； CYP2C19细胞株
Description描述：Yoruba from Ibadan, Nigeria; all four grandparents are Yoruba; donor subject has a single bp (G-to-A) transition at nucleotide 681 in exon 5 of the CYP2C19 gene (CYP2C19*2) which creates an aberrant splice site. The change altered the reading frame of the mRNA starting with amino acid 215 and produced a premature stop codon 20 amino acids downstream, resulting in a truncated, nonfunctional protein. Because of the aberrant splice site, a 40-bp deletion occurred at the beginning of exon 5 (from bp 643 to bp 682), resulting in deletion of amino acids 215 to 227. The truncated protein had 234 amino acids and would be catalytically inactive because it lacked the heme-binding region.
Category分类：B-Lymphocyte
ID编号:NTCC®-GM19203
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race:
Age年龄:
Gender性别:Male
Cell Type细胞类型: YORUBA IN IBADAN, NIGERIA | CYTOCHROME P450, SUBFAMILY IIC, POLYPEPTIDE 19; CYP2C19
Affected State:
Product:LCL
Gene:
Mutations突变:
Ethnicity:
Family:Y048
Relationship:father
Karyotype:
Tissue Type组织来源:Blood
Complete Growth Medium完全培养基: BioVector® Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
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