GM11024 MUSCULAR DYSTROPHY, DUCHENNE TYPE; DMD | TRANSLOCATED CHROMOSOME B-Lymphocyte Cell Line NTCC®细胞株-BioVector NTCC细胞库

Name细胞名称：NTCC® GM11024 MUSCULAR DYSTROPHY, DUCHENNE TYPE; DMD | TRANSLOCATED CHROMOSOME B-Lymphocyte Cell Line
杜兴型肌营养不良症； DMD |易位染色体细胞株
Description描述：Clinically affected female; X/autosome de novo balanced chromosome translocation; normal X chromosome is late replicating; negative family history; hypotonia; delayed milestones; microcephaly; performance IQ of 22; flat-footed, slapping gait; positive Gower's sign; calf hypertrophy; diminished reflexes; marked proximal muscle weakness of hips and shoulder girdles; at age 14 showed signs of a spastic diplegia with hyperreflexia and ankle clonus; flexion contractures of both elbows; EMG showed evidence of myopathy; muscle biopsy showed changes reflecting a severe active necrotizing myopathy; elevated CPK ranging from 40 to 28,000 over the course of 13 years; no dystrophin gene deletion/duplication detectable by PCR.
Category分类：B-Lymphocyte
ID编号:NTCC®-GM11024
Size/Quantity数量: 1 Flask/2 Vials
Biosafety Level生物安全级别:1
Shipping Info运输方式: RT/Dry Ice
Storage储存方式: RT/Liquid Nitrogen
Race: White
Age年龄:14 YR
Gender性别:Female
Cell Type细胞类型: MUSCULAR DYSTROPHY, DUCHENNE TYPE; DMD | TRANSLOCATED CHROMOSOME
Affected State:Yes
Product:LCL
Gene:
Mutations突变:
Ethnicity:
Family:
Relationship:proband
Karyotype:46,X,t(X;2)(Xqter>Xp21.2::2q37> 2qter;2pter>2q37::Xp21.2>Xpter)
Tissue Type组织来源:Blood
Complete Growth Medium完全培养基: BioVector® Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent Complete Medium
Subculturing传代方法:
Cryopreservation冻存方法:Freeze medium: Complete growth medium supplemented with 5% (v/v) DMSO
Storage temperature: liquid nitrogen vapor phase
Culture Conditions培养条件:Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Temperature: 37.0°C
STR Profile鉴定数据:
References参考文献:

Supplier供应商:BioVector质粒载体菌株细胞蛋白抗体基因保藏中心
NTCC典型培养物保藏中心
Tel电话：400-800-2947
Email：Biovector@163.com
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