Human Podocyte Cell Line (CIHP-1) cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心
- 价 格：¥98965
- 货 号：Human Podocyte Cell Line (CIHP-1)
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作QQ:1843439339 (微信同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
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BioVector® NTCC® Human Podocyte Cell Line (CIHP-1) cell line细胞株
Host HumanTissue KidneyModel Primary lineRelevance CIHP-1 cell line to study the maturation of podocytes in-vivo.Background and Research ApplicationThe Human Podocyte Cell Line (CIHP-1) is a primary cell line isolated from human kidney. Podocytes are highly specialised, terminally differentiated cells with a complex cellular structure. They are a critical component of glomerular filtration. Cell cycle control, growth arrest and differentiation are key to the in-vivo biology of podocytes. The conditionally immortalised podocyte cell line allows an in-vitro process of maturation analogous to the development and maturation of podocytes in-vivo. The result is a homogenous, stable cell source that shows expression of key antigenic markers of differentiated in-vivo podocytes. These include the novel podocyte proteins nephrin, podocin, CD2AP and synaptopodin. This robust cell line is extensively characterised and validated, used worldwide with over 100 peer reviewed publications to date.Conditional Description Immortalization is conditional by use of a temperature-sensitive transgene encoding SV40LTResearch Area OtherRecommended Growing Conditions RPMI-1640, Insulin-Transferrin-Selenium, Foetal Bovine Serum (10% v/v), Pen/Strep medium at at 33°C or 37°C, 5% CO2.Notes Points of InterestApplications:Toxicology studiesMetabolismTherapeutic targetingRenal physiology R&DCo-culture studies (e.g 3D culture model)Key benefits:Primary human cell derivedPhysiologically relevant phenotype analogous to in-vivo differentiated renal cellsHomogenous, stable and long lastingConcentrationVial has between 1-5 million cells as standard, however this may vary.
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
Host HumanTissue KidneyModel Primary lineRelevance CIHP-1 cell line to study the maturation of podocytes in-vivo.Background and Research ApplicationThe Human Podocyte Cell Line (CIHP-1) is a primary cell line isolated from human kidney. Podocytes are highly specialised, terminally differentiated cells with a complex cellular structure. They are a critical component of glomerular filtration. Cell cycle control, growth arrest and differentiation are key to the in-vivo biology of podocytes. The conditionally immortalised podocyte cell line allows an in-vitro process of maturation analogous to the development and maturation of podocytes in-vivo. The result is a homogenous, stable cell source that shows expression of key antigenic markers of differentiated in-vivo podocytes. These include the novel podocyte proteins nephrin, podocin, CD2AP and synaptopodin. This robust cell line is extensively characterised and validated, used worldwide with over 100 peer reviewed publications to date.Conditional Description Immortalization is conditional by use of a temperature-sensitive transgene encoding SV40LTResearch Area OtherRecommended Growing Conditions RPMI-1640, Insulin-Transferrin-Selenium, Foetal Bovine Serum (10% v/v), Pen/Strep medium at at 33°C or 37°C, 5% CO2.Notes Points of InterestApplications:Toxicology studiesMetabolismTherapeutic targetingRenal physiology R&DCo-culture studies (e.g 3D culture model)Key benefits:Primary human cell derivedPhysiologically relevant phenotype analogous to in-vivo differentiated renal cellsHomogenous, stable and long lastingConcentrationVial has between 1-5 million cells as standard, however this may vary.
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
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