EB66 NTCC®疫苗和治疗性蛋白生产用鸭胚胎干细胞株duck embryonic stem cell-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
- 价 格:¥1998950
- 货 号:NTCC®-295 EB66
- 产 地:北京
- BioVector NTCC典型培养物保藏中心
- 联系人:Dr.Xu, Biovector NTCC Inc.
电话:400-800-2947 工作QQ:1843439339 (微信同号)
邮件:Biovector@163.com
手机:18901268599
地址:北京
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EB66 NTCC®疫苗和治疗性蛋白生产用鸭胚胎干细胞株duck embryonic stem cell-BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
The NTCC® EB66 cell line is a duck embryonic stem cell-derived cell line that has been developed as a platform for the production of vaccines and therapeutic proteins. It is considered a valuable tool in the biotechnology industry due to its unique characteristics and advantages.
Key characteristics of the NTCC® EB66 cell line:
Origin: Derived from duck embryonic stem cells
Advantages:
High growth rate: Short population doubling time, allowing for rapid cell expansion.
High cell density: Can reach very high cell densities in culture, increasing production yields.
Unique metabolic profile: Low ammonium and lactate accumulation, reducing the need for frequent media changes.
Reduced fucose content: Leads to enhanced antibody-dependent cellular cytotoxicity (ADCC) activity of therapeutic antibodies produced in this cell line.
Genetic stability: Maintained through the expression of telomerase, ensuring long-term culture stability.
Scalability: Can be easily scaled up for industrial production in bioreactors.
Applications of the EB66 cell line:
Vaccine production: Used for the production of a variety of human and veterinary vaccines, including influenza, rabies, and Zika virus vaccines.
Therapeutic protein production: Used for the production of therapeutic antibodies and other recombinant proteins.
Advantages of using the EB66 cell line:
Consistent product quality: The use of a well-characterized cell line ensures consistent product quality and reproducibility.
Reduced production costs: The high growth rate and scalability of the EB66 cell line can lead to reduced production costs.
Enhanced product efficacy: The reduced fucose content of antibodies produced in EB66 cells can lead to enhanced ADCC activity, improving their therapeutic efficacy.
Overall, the NTCC® EB66 cell line is a valuable tool for the production of vaccines and therapeutic proteins. Its unique characteristics and advantages make it a promising platform for the development of new and improved biopharmaceuticals.
NTCC® EB66 细胞系是一种来源于鸭胚胎干细胞的细胞系,已被开发为生产疫苗和治疗性蛋白的平台。由于其独特的特性和优势,它被认为是生物技术行业中一种有价值的工具。
NTCC®EB66 细胞系的关键特征:
起源: 源自鸭胚胎干细胞
优势:
高生长速率: 细胞倍增时间短,可快速扩增细胞。
高细胞密度: 在培养中可达到非常高的细胞密度,从而提高产量。
独特的代谢特征: 氨和乳酸积累较少,减少了频繁更换培养基的需求。
降低岩藻糖含量: 导致在该细胞系中产生的治疗性抗体的抗体依赖性细胞毒性 (ADCC) 活性增强。
遗传稳定性: 通过端粒酶的表达维持,确保长期培养稳定性。
可扩展性: 可在生物反应器中轻松放大生产。
EB66 细胞系的应用:
疫苗生产: 用于生产多种人类和兽用疫苗,包括流感、狂犬病和寨卡病毒疫苗。
治疗性蛋白生产: 用于生产治疗性抗体和其他重组蛋白。
使用 EB66 细胞系的优势:
一致的产品质量: 使用经过充分表征的细胞系可确保一致的产品质量和可重复性。
降低生产成本: EB66 细胞系的高生长速率和可扩展性可降低生产成本。
提高产品功效: 在 EB66 细胞中产生的抗体岩藻糖含量降低可提高 ADCC 活性,从而提高其治疗功效。
总的来说,NTCC® EB66 细胞系是生产疫苗和治疗性蛋白的有价值工具。其独特的特性和优势使其成为开发新型和改进型生物制药产品的有前途的平台。
生产厂家Supplier:
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
E-mail:BioVector@163.com
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