SUM1315MO2 NTCC®人乳腺癌细胞株human breast cancer cell line BioVector NTCC Inc.
- 价 格:¥59850
- 货 号:NTCC®-SUM1315MO2
- 产 地:北京
- BioVector NTCC典型培养物保藏中心
- 联系人:Dr.Xu, Biovector NTCC Inc.
电话:400-800-2947 工作QQ:1843439339 (微信同号)
邮件:Biovector@163.com
手机:18901268599
地址:北京
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SUM1315MO2 NTCC®人乳腺癌细胞株human breast cancer cell line
BioVector NTCC Inc.
SUM1315MO2 is a human breast cancer cell line characterized by its BRCA1 mutation. This specific mutation, 185delAG, leads to a loss of function of the BRCA1 protein, which is involved in DNA repair.
Key characteristics of SUM1315MO2 cells:
BRCA1 mutation: Carries a deleterious mutation in the BRCA1 gene.
DNA repair deficiency: Impaired DNA repair mechanisms, particularly homologous recombination.
Sensitivity to DNA-damaging agents: Increased sensitivity to DNA-damaging agents like PARP inhibitors and platinum-based chemotherapy drugs.
Potential for targeted therapy: A promising target for therapies that exploit the vulnerabilities of BRCA1-deficient tumors.
By studying SUM1315MO2 cells, researchers can gain valuable insights into the biology of BRCA1-deficient breast cancer and develop more effective targeted therapies for patients with this aggressive form of the disease.
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生产厂家Supplier:
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
E-mail:BioVector@163.com
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