首页 » ​KOPM-88 NTCC®人急性髓系白血病细胞株human acute myeloid leukemia (AML) cell line BioVector NTCC细胞保藏中心

​KOPM-88 NTCC®人急性髓系白血病细胞株human acute myeloid leukemia (AML) cell line BioVector NTCC细胞保藏中心

  • 价  格:¥99850
  • 货  号:NTCC® ​KOPM-88
  • 产  地:北京
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KOPM-88 NTCC®人急性髓系白血病细胞株human acute myeloid leukemia (AML) cell line

BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心


KOPM-88 is a cell line derived from an 11-year-old patient with acute myeloid leukemia (AML). It is characterized by a partial tandem duplication of the MLL gene, which is a common genetic abnormality in AML. KOPM-88 cells are sensitive to inhibition of DOT1L, a histone methyltransferase that is important for the development of MLL-rearranged leukemias. This makes KOPM-88 a valuable tool for studying the role of DOT1L in AML and for developing new treatments for this disease.


CommentsPopulation: Japanese.
Misspelling: KOMP88; Note=Occasionally.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DiseaseChildhood acute myeloid leukemia (NCIt: C9160)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cellMale
Age at sampling11Y
CategoryCancer cell line

MO-91 Acute Myeloid Leukemia w Minimal Differentiation Human Cell Line |  Sigma-Aldrich


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BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心

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