Clostridium novyi Type A产气荚膜梭菌 A 型BioVector™ 19402 NTCC典型培养物保藏中心

BioVector™ATCC 19402 is a strain of the bacterium Clostridium novyi Type A. It's a type strain, meaning it serves as the reference example for this species.

Key Characteristics

• Anaerobic: This bacterium is a strict anaerobe, meaning it cannot survive in the presence of oxygen. It requires specialized, oxygen-free conditions for handling and cultivation.

• Pathogenic: The strain was originally isolated from a case of gas gangrene. It produces toxin A, which is responsible for the severe tissue damage characteristic of this disease.

• Gram-Positive: It is a rod-shaped, Gram-positive bacterium.

• Biosafety Level 2: Due to its pathogenic nature, this strain requires a Biosafety Level 2 containment facility for safe handling.

Applications

The ATCC 19402 strain is a crucial resource for research and quality control in microbiology. Its main applications include:

• Medical Research: It's used to study the pathogenesis of gas gangrene and other clostridial infections, providing a model to understand how the bacterium causes disease.

• Toxin Studies: Researchers use this strain to investigate the structure and function of toxin A, which could lead to the development of new treatments or antitoxins.

• Quality Control: The strain is used to test the performance of microbiological media, stains, and diagnostic kits, particularly those designed for the identification of anaerobes.

ATCC 19402 是产气荚膜梭菌 A 型（Clostridium novyi Type A）的一个菌株。它是一种模式菌株，意味着它是该物种的参考范例。

主要特点

• 厌氧性: 这种细菌是严格的厌氧菌，意味着它不能在有氧环境下存活。其操作和培养需要专门的、无氧条件。

• 致病性: 该菌株最初是从一例气性坏疽病例中分离得到的。它能产生A 型毒素，该毒素是导致这种疾病特有严重组织损伤的原因。

• 革兰氏阳性: 它是一种杆状、革兰氏阳性细菌。

• 生物安全等级2: 由于其致病性，处理该菌株需要生物安全等级2的实验室设施。

应用

ATCC 19402 菌株是微生物学研究和质量控制的重要资源。其主要应用包括：

• 医学研究: 它被用于研究气性坏疽和其他梭菌感染的发病机制，为理解细菌如何致病提供了一个模型。

• 毒素研究: 研究人员利用该菌株来探究 A 型毒素的结构和功能，这有助于开发新的治疗方法或抗毒素。

• 质量控制: 该菌株被用于测试微生物培养基、染色剂和诊断试剂盒的性能，特别是那些为鉴定厌氧菌而设计的试剂。

BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心

BioVector NTCC Inc.

TEL: 400-800-2947, 189-0126-8599

E-mail: biovector@163.com

http://www.biovector.net