HyCyte MDA-MB-436 KO-hARTN人非特殊类型浸润性乳腺癌癌细胞株BioVector NTCC细胞保藏中心

[Designation名称] NTCC® HyCyte MDA-MB-436 KO-hARTN Cell Line细胞株
BioVector NTCC典型培养物保藏中心

Synonyms: hARTN knockout MDA-MB-436
Cross-references: Hysigen; CGKO-M3186
Comments: Group: Triple negative breast cancer (TNBC) cell line.
Comments: Population: Caucasian.
Comments: Doubling time: 60-72 hours (Hysigen=CGKO-M3186).
Comments: Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:727; ARTN.
Comments: Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; c.5277+1G>A; ClinVar=VCV000037654; Zygosity=Hemizygous; Note=Splice donor mutation (from parent cell line).
Comments: Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Gly203fs*9 (c.607_608ins227); Zygosity=Homozygous (from parent cell line).
Comments: Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu204fs*7 (c.610_612delinsGCGTGTGG); Zygosity=Unspecified (from parent cell line).
Comments: Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Diseases: C4194; Invasive breast carcinoma of no special type
Species of origin: NCBI_TaxID=9606; ! Homo sapiens (Human)
[Organism物种来源]
[Disease疾病种类]
[编号]Accession Number: NTCC® CVCL_F1RT
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培养方法：
Medium培养基：NTCC® HyCyte MDA-MB-436 KO-hARTN Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.
Atmosphere: 95% Air, 5% CO2

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