H9-iCas9-APPswe/swe细胞株NTCC® Cell Line BioVector细胞保藏中心
- 价 格：¥99850
- 货 号：H9-iCas9-APPswe/swe
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作微信:1843439339 (QQ同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
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[Designation名称] NTCC® H9-iCas9-APPswe/swe Cell Line细胞株
BioVector NTCC Inc.Synonyms细胞别名: ID H9-iCas9-APP(swe/swe)Comments: Characteristics: Cell line with robust Dox-inducible expression of Cas9 and an edited homozygous APP(Swe) mutation (PubMed=38917806).Accession Number: NTCC® CVCL_E7G5References identifiers: PubMed=38917806;Comments: Characteristics: Using TALEN two constructs SA-2A-HygR-Cas9-TRE and SA-2A-Neo-M2rtTA were introduced in the AAVS1 safe harbor locus, one in each allele (from parent cell line).Comments: Sequence variation: Mutation; HGNC; HGNC:620; APP; Simple_edited; p.Lys670_Met671delinsAsnLeu (c.2010_2011inv) (c.2010_2011delGAinsTC); ClinVar=VCV000018093; Zygosity=Homozygous; Note=By CRISPR/Cas9 (PubMed=38917806).Comments: Genetic integration: Method=TALEN; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).Comments: Genetic integration: Method=TALEN; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.Comments: Genetic integration: Method=TALEN; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.Comments: Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.Comments: Cell type: Embryonic stem cell; CL=CL_0002322.Diseases: C146894; Alzheimer's disease 1Diseases: Orphanet_1020; Early-onset autosomal dominant Alzheimer diseaseSpecies of origin: NCBI_TaxID=9606; ! Homo sapiens (Human)Hierarchy: CVCL_E7G4 ! H9-iCas9
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC®-Accession Number: NTCC® CVCL_E7G5
[Comments描述]
[Reference参考文献]
[Category分类]
[Date保藏时间]
[Hierarchy]
培养方法：
Medium培养基：NTCC® H9-iCas9-APPswe/swe Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.Atmosphere: 95% Air, 5% CO2
Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址：www.biovector.net
BioVector NTCC Inc.Synonyms细胞别名: ID H9-iCas9-APP(swe/swe)Comments: Characteristics: Cell line with robust Dox-inducible expression of Cas9 and an edited homozygous APP(Swe) mutation (PubMed=38917806).Accession Number: NTCC® CVCL_E7G5References identifiers: PubMed=38917806;Comments: Characteristics: Using TALEN two constructs SA-2A-HygR-Cas9-TRE and SA-2A-Neo-M2rtTA were introduced in the AAVS1 safe harbor locus, one in each allele (from parent cell line).Comments: Sequence variation: Mutation; HGNC; HGNC:620; APP; Simple_edited; p.Lys670_Met671delinsAsnLeu (c.2010_2011inv) (c.2010_2011delGAinsTC); ClinVar=VCV000018093; Zygosity=Homozygous; Note=By CRISPR/Cas9 (PubMed=38917806).Comments: Genetic integration: Method=TALEN; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).Comments: Genetic integration: Method=TALEN; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.Comments: Genetic integration: Method=TALEN; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.Comments: Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.Comments: Cell type: Embryonic stem cell; CL=CL_0002322.Diseases: C146894; Alzheimer's disease 1Diseases: Orphanet_1020; Early-onset autosomal dominant Alzheimer diseaseSpecies of origin: NCBI_TaxID=9606; ! Homo sapiens (Human)Hierarchy: CVCL_E7G4 ! H9-iCas9
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC®-Accession Number: NTCC® CVCL_E7G5
[Comments描述]
[Reference参考文献]
[Category分类]
[Date保藏时间]
[Hierarchy]
培养方法：
Medium培养基：NTCC® H9-iCas9-APPswe/swe Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.Atmosphere: 95% Air, 5% CO2
Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址：www.biovector.net
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