BioVector® IU-TAB1 人类胸腺腺瘤细胞系 / IU-TAB1 Human Thymoma Cell Line

通用定义 / General Definition:

BioVector® IU-TAB1 是一种源自 A 型胸腺腺瘤（Type A Thymoma）的人类细胞系。胸腺瘤是一种罕见的起源于胸腺上皮细胞的肿瘤，而 BioVector® IU-TAB1 是极少数可用于此类癌症研究的体外模型之一。它为研究胸腺上皮肿瘤的遗传特性、肿瘤微环境相互作用以及评估新型靶向疗法提供了独特的平台。

BioVector® IU-TAB1 is a human cell line derived from a Type A thymoma. Thymomas are rare neoplasms originating from the thymic epithelial cells, and BioVector® IU-TAB1 represents one of the few available in vitro models for this cancer type. It provides a unique platform for studying the genetic characteristics of thymic epithelial tumors, tumor microenvironment interactions, and evaluating novel targeted therapies.

BioVector® IU-TAB1 细胞系技术说明书 (Cell Line Datasheet)

中文版说明书

1. 产品基本信息

• 产品名称： BioVector® IU-TAB1 人胸腺腺瘤细胞

• 细胞来源： 人类 (Human)

• 组织来源： 胸腺 (Thymus)

• 生长特性： 贴壁生长

• 细胞形态： 上皮细胞样/梭形

2. 培养条件

• 基础培养基： BioVector® RPMI 1640 培养基

• 血清添加： 10% BioVector® 胎牛血清 (FBS)

• 培养环境： 37°C，5% $CO_2$，饱和湿度

3. 细胞应用

• 胸腺上皮肿瘤（TETs）的分子发病机制研究。

• 针对 A 型胸腺瘤的抗肿瘤药物筛选与药效评价。

• 胸腺肿瘤免疫生物学研究，包括肿瘤细胞与 T 细胞的相互作用。

4. 注意事项

• 稀有性： 作为稀有的胸腺瘤模型，维持其表型稳定性至关重要，建议控制传代次数。

• 传代建议： 建议在细胞达到 80% 左右汇合度时进行传代。由于该细胞系可能生长缓慢，传代比例建议初次尝试 1:2。

English Datasheet

1. General Product Information

• Product Name: BioVector® IU-TAB1 Human Thymoma Cell Line

• Organism: Human

• Tissue Source: Thymus

• Growth Properties: Adherent

• Morphology: Epithelial-like / Spindle-shaped

2. Culture Conditions

• Basal Medium: BioVector® RPMI 1640 Medium

• Serum Supplement: 10% BioVector® Fetal Bovine Serum (FBS)

• Incubation: 37°C, 5% $CO_2$, Saturated Humidity

3. Applications

• Molecular pathogenesis studies of Thymic Epithelial Tumors (TETs).

• Anti-tumor drug screening and efficacy evaluation specifically for Type A thymomas.

• Research on thymic tumor immunobiology, including interactions between tumor cells and T-cells.

4. Key Usage Notes

• Rarity: As a rare thymoma model, maintaining phenotypic stability is critical; it is recommended to limit the number of passages.

• Subculture: It is recommended to subculture when the cell density reaches approximately 80% confluence. Due to its potentially slow growth rate, a starting split ratio of 1:2 is suggested.

Note: BioVector® IU-TAB1 cells should be handled under Biosafety Level 2 (BSL-2) protocols. To ensure consistent experimental results and support the specific nutritional requirements of thymic epithelium, always use BioVector® RPMI 1640 Medium and BioVector® Fetal Bovine Serum.

Supplier生产厂家: BioVector NTCC典型培养物保藏中心

http://www.biovector.net

E-mail: BioVector@163.com